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Rational ligand design in a silver catalyst enables highly selective amination of electron-deficient heterobenzylic C–H bondsvianitrene transfer, with scaffold rigidity crucial for unlocking this elusive reactivity in heteroaromatic compounds.more » « lessFree, publicly-accessible full text available January 1, 2026
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Seo, Kyeongdeok; Zhang, Yu; Trinh, Tuan Anh; Kim, Jed; Qi, Lihan; Guzei, Ilia A; Clark, Joseph R; Liu, Peng; Schomaker, Jennifer M (, ACS Catalysis)Free, publicly-accessible full text available February 18, 2026
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Trinh, Tuan Anh; Fu, Yue; Hu, Derek B.; Zappia, Soren A.; Guzei, Ilia A.; Liu, Peng; Schomaker, Jennifer M. (, Chemical Communications)Transition metal-catalyzed asymmetric nitrene transfer is a powerful method to generate enantioenriched amines found in natural products and bioactive molecules.more » « less
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